Effects of corticosterone on neurones of the locus coeruleus, in the rat

Gian Luigi Avanzino; Rosa Ermirio; Carla E. Cogo; Piero Ruggeri; Claudio Molinari

doi:10.1016/0304-3940(87)90500-3

Effects of corticosterone on neurones of the locus coeruleus, in the rat

Gian Luigi Avanzino
, Rosa Ermirio
, Carla E. Cogo
, Piero Ruggeri
, Claudio Molinari

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of microelectrophoretic application of corticosterone (CS) on single neurones of the locus coeruleus (LC) were investigated in rats under urethane anaesthesia. Ejecting currents generally ranged from 10 to 60 nA. CS produced an excitatory effect in 73% of the neurones and no effect in 27%. The prevailingly excitatory effects induced by CS on LC neurones may be related to the regulation of those complex events, which constitute the 'stress response'.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Neuroscience Letters
Volume	80
Issue number	1
DOIs	https://doi.org/10.1016/0304-3940(87)90500-3
Publication status	Published - 11 Sept 1987
Externally published	Yes

Keywords

Brainstem
Corticosterone
Glucocorticoid hormone
Locus coeruleus
Microelectrophoresis
Stress

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10.1016/0304-3940(87)90500-3

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title = "Effects of corticosterone on neurones of the locus coeruleus, in the rat",

abstract = "The effects of microelectrophoretic application of corticosterone (CS) on single neurones of the locus coeruleus (LC) were investigated in rats under urethane anaesthesia. Ejecting currents generally ranged from 10 to 60 nA. CS produced an excitatory effect in 73\% of the neurones and no effect in 27\%. The prevailingly excitatory effects induced by CS on LC neurones may be related to the regulation of those complex events, which constitute the 'stress response'.",

keywords = "Brainstem, Corticosterone, Glucocorticoid hormone, Locus coeruleus, Microelectrophoresis, Stress",

author = "Avanzino, \{Gian Luigi\} and Rosa Ermirio and Cogo, \{Carla E.\} and Piero Ruggeri and Claudio Molinari",

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doi = "10.1016/0304-3940(87)90500-3",

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T1 - Effects of corticosterone on neurones of the locus coeruleus, in the rat

AU - Avanzino, Gian Luigi

AU - Ermirio, Rosa

AU - Cogo, Carla E.

AU - Ruggeri, Piero

AU - Molinari, Claudio

PY - 1987/9/11

Y1 - 1987/9/11

N2 - The effects of microelectrophoretic application of corticosterone (CS) on single neurones of the locus coeruleus (LC) were investigated in rats under urethane anaesthesia. Ejecting currents generally ranged from 10 to 60 nA. CS produced an excitatory effect in 73% of the neurones and no effect in 27%. The prevailingly excitatory effects induced by CS on LC neurones may be related to the regulation of those complex events, which constitute the 'stress response'.

AB - The effects of microelectrophoretic application of corticosterone (CS) on single neurones of the locus coeruleus (LC) were investigated in rats under urethane anaesthesia. Ejecting currents generally ranged from 10 to 60 nA. CS produced an excitatory effect in 73% of the neurones and no effect in 27%. The prevailingly excitatory effects induced by CS on LC neurones may be related to the regulation of those complex events, which constitute the 'stress response'.

KW - Brainstem

KW - Corticosterone

KW - Glucocorticoid hormone

KW - Locus coeruleus

KW - Microelectrophoresis

KW - Stress

UR - https://www.scopus.com/pages/publications/0023184746

U2 - 10.1016/0304-3940(87)90500-3

DO - 10.1016/0304-3940(87)90500-3

M3 - Article

SN - 0304-3940

VL - 80

SP - 85

EP - 88

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 1

ER -

Effects of corticosterone on neurones of the locus coeruleus, in the rat

Abstract

Keywords

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