Effect of propylene glycol and ethanol on the UVB-induced peroxidation of linoleic acid and lipids of porcine skin, in the presence of different TiO2 specimens

M. E. Carlotti; E. Ugazio; S. Sapino; D. Vione; B. Fubini; S. Morel

doi:10.1080/01932690903224615

Effect of propylene glycol and ethanol on the UVB-induced peroxidation of linoleic acid and lipids of porcine skin, in the presence of different TiO₂ specimens

M. E. Carlotti, E. Ugazio, S. Sapino, D. Vione, B. Fubini, S. Morel

Department of Drug Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Titanium dioxide is a sunscreen pigment with photocatalytic activity. We studied the behavior of different TiO₂ specimens used in cosmetic products on the UVB-induced peroxidation of linoleic acid as model substrate and of porcine skin, at different pH values. Lipoperoxidation of linoleic acid occurred to a lower extent with the coated compared to the uncoated TiO₂, and it decreased at pH 7.0 compared to 4.0. The addition of organic additives such as propylene glycol and ethanol induced a significant reduction of the lipoperoxidation activity, particularly with the most reactive TiO₂ specimens. Similar results were obtained with the porcine skin.

Original language	English
Pages (from-to)	994-1003
Number of pages	10
Journal	Journal of Dispersion Science and Technology
Volume	31
Issue number	7
DOIs	https://doi.org/10.1080/01932690903224615
Publication status	Published - Jun 2010

Keywords

Ethanol
Linoleic acid
Porcine skin
Propylene glycol
TiO nanoparticles
UVB irradiation

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10.1080/01932690903224615

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title = "Effect of propylene glycol and ethanol on the UVB-induced peroxidation of linoleic acid and lipids of porcine skin, in the presence of different TiO2 specimens",

abstract = "Titanium dioxide is a sunscreen pigment with photocatalytic activity. We studied the behavior of different TiO2 specimens used in cosmetic products on the UVB-induced peroxidation of linoleic acid as model substrate and of porcine skin, at different pH values. Lipoperoxidation of linoleic acid occurred to a lower extent with the coated compared to the uncoated TiO2, and it decreased at pH 7.0 compared to 4.0. The addition of organic additives such as propylene glycol and ethanol induced a significant reduction of the lipoperoxidation activity, particularly with the most reactive TiO2 specimens. Similar results were obtained with the porcine skin.",

keywords = "Ethanol, Linoleic acid, Porcine skin, Propylene glycol, TiO nanoparticles, UVB irradiation",

author = "Carlotti, {M. E.} and E. Ugazio and S. Sapino and D. Vione and B. Fubini and S. Morel",

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T1 - Effect of propylene glycol and ethanol on the UVB-induced peroxidation of linoleic acid and lipids of porcine skin, in the presence of different TiO2 specimens

AU - Carlotti, M. E.

AU - Ugazio, E.

AU - Sapino, S.

AU - Vione, D.

AU - Fubini, B.

AU - Morel, S.

PY - 2010/6

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AB - Titanium dioxide is a sunscreen pigment with photocatalytic activity. We studied the behavior of different TiO2 specimens used in cosmetic products on the UVB-induced peroxidation of linoleic acid as model substrate and of porcine skin, at different pH values. Lipoperoxidation of linoleic acid occurred to a lower extent with the coated compared to the uncoated TiO2, and it decreased at pH 7.0 compared to 4.0. The addition of organic additives such as propylene glycol and ethanol induced a significant reduction of the lipoperoxidation activity, particularly with the most reactive TiO2 specimens. Similar results were obtained with the porcine skin.

KW - Ethanol

KW - Linoleic acid

KW - Porcine skin

KW - Propylene glycol

KW - TiO nanoparticles

KW - UVB irradiation

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Effect of propylene glycol and ethanol on the UVB-induced peroxidation of linoleic acid and lipids of porcine skin, in the presence of different TiO₂ specimens

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