Double-Drug Regimen Using GnRH Analogues

S Ferrero; LH Abbamonte; M Parisi; N Ragni; VALENTINO REMORGIDA

Double-Drug Regimen Using GnRH Analogues

S Ferrero, LH Abbamonte, M Parisi, N Ragni, VALENTINO REMORGIDA

Department of Translational Medicine

Research output: Contribution to conference › Paper

Abstract

Numerous clinical trials demonstrated that the optimal log-term treatment of pelvic pain caused by endometriosis may involve the use of GnRH ana- logues (GnRH-a) to suppress ovarian estrogen production combined with add- back low doses of estrogen plus progestin or progestin only. Estrogen, as a solitary add back, is less effective and thus is not indicated. Tibolone can be used as add back therapy to prevent hypoestrogenic symptoms. Recently, the post-operative administration of GnRH-a and anastrozole have been suggested to increase the pain-free interval and decrease symptom recurrence rates in patients following surgery for severe endometriosis.

Original language	English
Pages	15-18
Number of pages	4
Publication status	Published - 1 Jan 2006
Event	The world meeting on gynecological pelvic pain and endometriosis - Milan Duration: 1 Jan 2006 → …

Conference

Conference	The world meeting on gynecological pelvic pain and endometriosis
City	Milan
Period	1/01/06 → …

Keywords

Endometriosis
gnrh analogue
hormonal therapy

Cite this

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title = "Double-Drug Regimen Using GnRH Analogues",

abstract = "Numerous clinical trials demonstrated that the optimal log-term treatment of pelvic pain caused by endometriosis may involve the use of GnRH ana- logues (GnRH-a) to suppress ovarian estrogen production combined with add- back low doses of estrogen plus progestin or progestin only. Estrogen, as a solitary add back, is less effective and thus is not indicated. Tibolone can be used as add back therapy to prevent hypoestrogenic symptoms. Recently, the post-operative administration of GnRH-a and anastrozole have been suggested to increase the pain-free interval and decrease symptom recurrence rates in patients following surgery for severe endometriosis.",

keywords = "Endometriosis, gnrh analogue, hormonal therapy, Endometriosis, gnrh analogue, hormonal therapy",

author = "S Ferrero and LH Abbamonte and M Parisi and N Ragni and VALENTINO REMORGIDA",

year = "2006",

month = jan,

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language = "English",

pages = "15--18",

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TY - CONF

T1 - Double-Drug Regimen Using GnRH Analogues

AU - Ferrero, S

AU - Abbamonte, LH

AU - Parisi, M

AU - Ragni, N

AU - REMORGIDA, VALENTINO

PY - 2006/1/1

Y1 - 2006/1/1

N2 - Numerous clinical trials demonstrated that the optimal log-term treatment of pelvic pain caused by endometriosis may involve the use of GnRH ana- logues (GnRH-a) to suppress ovarian estrogen production combined with add- back low doses of estrogen plus progestin or progestin only. Estrogen, as a solitary add back, is less effective and thus is not indicated. Tibolone can be used as add back therapy to prevent hypoestrogenic symptoms. Recently, the post-operative administration of GnRH-a and anastrozole have been suggested to increase the pain-free interval and decrease symptom recurrence rates in patients following surgery for severe endometriosis.

AB - Numerous clinical trials demonstrated that the optimal log-term treatment of pelvic pain caused by endometriosis may involve the use of GnRH ana- logues (GnRH-a) to suppress ovarian estrogen production combined with add- back low doses of estrogen plus progestin or progestin only. Estrogen, as a solitary add back, is less effective and thus is not indicated. Tibolone can be used as add back therapy to prevent hypoestrogenic symptoms. Recently, the post-operative administration of GnRH-a and anastrozole have been suggested to increase the pain-free interval and decrease symptom recurrence rates in patients following surgery for severe endometriosis.

KW - Endometriosis

KW - gnrh analogue

KW - hormonal therapy

KW - Endometriosis

KW - gnrh analogue

KW - hormonal therapy

UR - https://iris.uniupo.it/handle/11579/118029

M3 - Paper

SP - 15

EP - 18

T2 - The world meeting on gynecological pelvic pain and endometriosis

Y2 - 1 January 2006

ER -

Double-Drug Regimen Using GnRH Analogues

Abstract

Conference

Keywords

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