De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients

Pierfrancesco Franco; Giuseppe Carlo Iorio; Sara Bartoncini; Mario Airoldi; Corrado De Sanctis; Isabella Castellano; Umberto Ricardi

doi:10.1007/s12032-018-1121-8

De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients

Pierfrancesco Franco
, Giuseppe Carlo Iorio
, Sara Bartoncini
, Mario Airoldi
, Corrado De Sanctis
, Isabella Castellano
, Umberto Ricardi

Research output: Contribution to journal › Review article › peer-review

Abstract

The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.

Original language	English
Article number	62
Journal	Medical Oncology
Volume	35
Issue number	5
DOIs	https://doi.org/10.1007/s12032-018-1121-8
Publication status	Published - 1 May 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Accelerated partial breast irradiation
Boost
Breast cancer
De-escalation
Hypofractionation
Radiotherapy omission
Whole-breast radiation

Access to Document

10.1007/s12032-018-1121-8

Cite this

@article{fa0b20091db34247b83d1dd22f38030f,

title = "De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients",

abstract = "The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.",

keywords = "Accelerated partial breast irradiation, Boost, Breast cancer, De-escalation, Hypofractionation, Radiotherapy omission, Whole-breast radiation",

author = "Pierfrancesco Franco and Iorio, \{Giuseppe Carlo\} and Sara Bartoncini and Mario Airoldi and \{De Sanctis\}, Corrado and Isabella Castellano and Umberto Ricardi",

note = "Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2018",

month = may,

day = "1",

doi = "10.1007/s12032-018-1121-8",

language = "English",

volume = "35",

journal = "Medical Oncology",

issn = "1357-0560",

publisher = "Springer",

number = "5",

}

TY - JOUR

T1 - De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients

AU - Franco, Pierfrancesco

AU - Iorio, Giuseppe Carlo

AU - Bartoncini, Sara

AU - Airoldi, Mario

AU - De Sanctis, Corrado

AU - Castellano, Isabella

AU - Ricardi, Umberto

PY - 2018/5/1

Y1 - 2018/5/1

N2 - The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.

AB - The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.

KW - Accelerated partial breast irradiation

KW - Boost

KW - Breast cancer

KW - De-escalation

KW - Hypofractionation

KW - Radiotherapy omission

KW - Whole-breast radiation

UR - https://www.scopus.com/pages/publications/85044957745

U2 - 10.1007/s12032-018-1121-8

DO - 10.1007/s12032-018-1121-8

M3 - Review article

SN - 1357-0560

VL - 35

JO - Medical Oncology

JF - Medical Oncology

IS - 5

M1 - 62

ER -

De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this