Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia

Riccardo Moia; Mariangela Greco; Paola Boggione; Maura Nicolosi; Riccardo Bruna; Andrea Patriarca; Gianluca Gaidano; Monia Lunghi

doi:10.1002/ccr3.3114

Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia

Riccardo Moia
, Mariangela Greco
, Paola Boggione
, Maura Nicolosi
, Riccardo Bruna
, Andrea Patriarca
, Gianluca Gaidano
, Monia Lunghi

Department of Translational Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Patients with B-lineage acute lymphoblastic leukemia treated with pegasparaginase-containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

Original language	English
Pages (from-to)	2293-2294
Number of pages	2
Journal	Clinical Case Reports
Volume	8
Issue number	11
DOIs	https://doi.org/10.1002/ccr3.3114
Publication status	Published - Nov 2020

Keywords

ALL
CSF xanthochromia
hepatotoxicity
pegasparaginase

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10.1002/ccr3.3114

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title = "Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia",

abstract = "Patients with B-lineage acute lymphoblastic leukemia treated with pegasparaginase-containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.",

keywords = "ALL, CSF xanthochromia, hepatotoxicity, pegasparaginase",

author = "Riccardo Moia and Mariangela Greco and Paola Boggione and Maura Nicolosi and Riccardo Bruna and Andrea Patriarca and Gianluca Gaidano and Monia Lunghi",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors. Clinical Case Reports published by John Wiley \& Sons Ltd.",

year = "2020",

month = nov,

doi = "10.1002/ccr3.3114",

language = "English",

volume = "8",

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TY - JOUR

T1 - Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia

AU - Moia, Riccardo

AU - Greco, Mariangela

AU - Boggione, Paola

AU - Nicolosi, Maura

AU - Bruna, Riccardo

AU - Patriarca, Andrea

AU - Gaidano, Gianluca

AU - Lunghi, Monia

PY - 2020/11

Y1 - 2020/11

N2 - Patients with B-lineage acute lymphoblastic leukemia treated with pegasparaginase-containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

AB - Patients with B-lineage acute lymphoblastic leukemia treated with pegasparaginase-containing regimens can develop hepatotoxicity related to it. The systemic hyperbilirubinemia due to hepatotoxicity can lead to the development of CSF xanthochromia.

KW - ALL

KW - CSF xanthochromia

KW - hepatotoxicity

KW - pegasparaginase

UR - https://www.scopus.com/pages/publications/85088033479

U2 - 10.1002/ccr3.3114

DO - 10.1002/ccr3.3114

M3 - Article

SN - 2050-0904

VL - 8

SP - 2293

EP - 2294

JO - Clinical Case Reports

JF - Clinical Case Reports

IS - 11

ER -

Cerebrospinal fluid xanthochromia after pegasparaginase hepatotoxicity in B-cell acute lymphoblastic leukemia

Abstract

Keywords

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