Bifunctional ligands based on the DOTA-monoamide cage

A BARGE; LORENZO TEI; D UPADHYAYA; F FEDELI; L BELTRAMI; Rachele STEFANIA; S AIME; G. CRAVOTTO

Bifunctional ligands based on the DOTA-monoamide cage

A BARGE
, LORENZO TEI
, D UPADHYAYA
, F FEDELI
, L BELTRAMI
, Rachele STEFANIA
, S AIME
, G. CRAVOTTO

Department of Science and Technological Innovation

Research output: Contribution to journal › Article › peer-review

Abstract

Efficient routes to DOTA-monoamide ligands bearing amino, hydroxyl, aldehyde and maleimido groups are described. These functional groups, which can be spaced at will from the coordination cage, will readily react with suitable groups of targeting moieties. Bioconjugates obtained in this way can be used for diagnostic imaging and therapeutic applications.

Original language	English
Pages (from-to)	1176-1184
Number of pages	9
Journal	Organic and Biomolecular Chemistry
Volume	6
Publication status	Published - 2008

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http://hdl.handle.net/11579/25820

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title = "Bifunctional ligands based on the DOTA-monoamide cage",

abstract = "Efficient routes to DOTA-monoamide ligands bearing amino, hydroxyl, aldehyde and maleimido groups are described. These functional groups, which can be spaced at will from the coordination cage, will readily react with suitable groups of targeting moieties. Bioconjugates obtained in this way can be used for diagnostic imaging and therapeutic applications.",

author = "A BARGE and LORENZO TEI and D UPADHYAYA and F FEDELI and L BELTRAMI and Rachele STEFANIA and S AIME and G. CRAVOTTO",

year = "2008",

language = "English",

volume = "6",

pages = "1176--1184",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Bifunctional ligands based on the DOTA-monoamide cage

AU - BARGE, A

AU - TEI, LORENZO

AU - UPADHYAYA, D

AU - FEDELI, F

AU - BELTRAMI, L

AU - STEFANIA, Rachele

AU - AIME, S

AU - CRAVOTTO, G.

PY - 2008

Y1 - 2008

N2 - Efficient routes to DOTA-monoamide ligands bearing amino, hydroxyl, aldehyde and maleimido groups are described. These functional groups, which can be spaced at will from the coordination cage, will readily react with suitable groups of targeting moieties. Bioconjugates obtained in this way can be used for diagnostic imaging and therapeutic applications.

AB - Efficient routes to DOTA-monoamide ligands bearing amino, hydroxyl, aldehyde and maleimido groups are described. These functional groups, which can be spaced at will from the coordination cage, will readily react with suitable groups of targeting moieties. Bioconjugates obtained in this way can be used for diagnostic imaging and therapeutic applications.

UR - https://iris.uniupo.it/handle/11579/25820

M3 - Article

SN - 1477-0520

VL - 6

SP - 1176

EP - 1184

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

ER -

Bifunctional ligands based on the DOTA-monoamide cage

Abstract

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