Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands

Keyphrases

• Human Monocytes 100%
• Monocyte-derived Macrophages 100%
• Monocyte-derived Microparticle 100%
• PPAR Ligands 100%
• Microparticles 71%
• Nuclear factor-κB 42%
• Cytokine Release 42%
• Protein Expression 28%
• Prostaglandins 28%
• Phorbol 12-myristate 13-acetate 28%
• Rosiglitazone 28%
• Superoxide Anion Production 28%
• PPAR Antagonist 28%
• PPAR Agonists 28%
• Inflammation 14%
• Apoptosis 14%
• Concentration-dependent 14%
• Pathophysiological Conditions 14%
• Immunoblotting 14%
• Intercellular Communication 14%
• Procoagulant Activity 14%
• Supernatant 14%
• Membrane Binding 14%
• Healthy Donors 14%
• Calcium Ionophore A23187 14%
• Human Macrophages 14%
• Expression Effects 14%
• Autocrine Effect 14%
• Oxygen Radical Production 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Microparticle 100%
• Peroxisome Proliferator Activated Receptor 100%
• Cytokine 30%
• Superoxide 20%
• 12-O-Tetradecanoylphorbol-13-Acetate 20%
• Prostaglandin 20%
• Rosiglitazone 20%
• Peroxisome Proliferator Activated Receptor Antagonist 20%
• PPAR Agonist 20%
• Calcimycin 10%
• Western Blot 10%
• Inflammation 10%
• Anti-Inflammatory Drug 10%
• Oxygen Radical 10%
• Electrophoretic Mobility Shift Assay 10%
• Procoagulant 10%