Artesunate protects against the organ injury and dysfunction induced by severe hemorrhage and resuscitation

Keyphrases

• Organ Damage 100%
• Organ Dysfunction 100%
• Resuscitation 100%
• Massive Hemorrhage 100%
• Artesunate 100%
• Hemorrhagic Shock 70%
• Nuclear factor-κB 20%
• Endothelial Nitric Oxide Synthase (eNOS) 20%
• Glycogen Synthase kinase-3β (GSK-3β) 20%
• Survival Pathways 20%
• Interleukin-6 10%
• Western Blot Analysis 10%
• Induced Activation 10%
• Phosphorylation 10%
• Cause of Death 10%
• Mean Arterial Pressure 10%
• Anti-inflammatory Effect 10%
• Tumor Necrosis Factor-α 10%
• Multiple Organ Failure 10%
• Common Cause 10%
• Systemic Inflammatory Response 10%
• Pharmacological Activities 10%
• Multiple Organ Dysfunction 10%
• Inducible Nitric Oxide Synthase 10%
• RNA Sequencing (RNA-seq) 10%
• Path Analysis 10%
• Phase I Trial 10%
• Protein Kinase B 10%
• Anticancer 10%
• Shock-induced 10%
• Antimalarial Activity 10%
• IL-1 Receptor-associated Kinase 1 (IRAK1) 10%
• Trauma-hemorrhage 10%
• Multiple Organ Injury 10%
• Good Manufacturing Practice 10%
• Severely Injured Patients 10%
• Patient-specific Treatment 10%
• Organ Perfusion 10%
• Pro-inflammatory Proteins 10%
• Phosphorylation Activation 10%
• Patients with Trauma 10%

Medicine and Dentistry

• Resuscitation 100%
• Organ Injury 100%
• Organ Dysfunction 100%
• Bleeding 100%
• Artesunate 100%
• Hemorrhagic Shock 70%
• Protein Kinase B 40%
• Endothelial Nitric Oxide Synthase 20%
• Immunoglobulin Enhancer Binding Protein 20%
• Glycogen Synthase Kinase 20%
• Serositis 10%
• Antivirus Agent 10%
• Clinical Trial 10%
• Interleukin 6 10%
• Western Blot 10%
• Mean Arterial Pressure 10%
• Tumor Necrosis Factor 10%
• Downregulation 10%
• Multiple Organ Dysfunction Syndrome 10%
• Inducible Nitric Oxide Synthase 10%
• Antiinflammatory Activity 10%
• RNA Sequence 10%
• Drug Action 10%
• phosphorylation 10%
• Antimalarial Activity 10%
• Phosphorylation Inhibition 10%
• Interleukin 1 Receptor Associated Kinase 1 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Organ Injury 100%
• Artesunate 100%
• Hemorrhagic Shock 70%
• Protein Kinase B 40%
• Rat 40%
• Endothelial Nitric Oxide Synthase 20%
• Immunoglobulin Enhancer Binding Protein 20%
• Glycogen Synthase Kinase 20%
• Glycogen Synthase Kinase 3 20%
• Clinical Trial 10%
• Drug Action 10%
• Tumor Necrosis Factor 10%
• Western Blot 10%
• Antivirus Agent 10%
• Inflammation 10%
• Interleukin 6 10%
• Multiple Organ Failure 10%
• Inducible Nitric Oxide Synthase 10%
• Antiinflammatory Activity 10%
• Antimalarial Activity 10%
• Interleukin 1 Receptor Associated Kinase 1 10%
• Good Manufacturing Practice 10%