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ARHGDIA, a mutant TP53-associated Rho GDP dissociation inhibitor, is over-expressed in gene expression profiles of TP53 disrupted chronic lymphocytic leukaemia cells

  • Michele Dal Bo
  • , Federico Pozzo
  • , Riccardo Bomben
  • , Massimo Degan
  • , Daniela Marconi
  • , Antonella Zucchetto
  • , Davide Rossi
  • , Gabriele Pozzato
  • , Giorgio Zauli
  • , Gianluca Gaidano
  • , Giovanni Del Poeta
  • , Valter Gattei

Research output: Contribution to journalLetterpeer-review

Abstract

The gene expression signature associated with TP53 mutation/deletion in chronic lymphocytic leukaemia is dominated by the under-expression of TP53 and other genes on chromosome 17p.
Original languageEnglish
Pages (from-to)596-599
Number of pages4
JournalBritish Journal of Haematology
Volume161
Issue number4
DOIs
Publication statusPublished - May 2013

Keywords

  • CLL
  • Chemosensitivity
  • TP53

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