ARHGDIA, a mutant TP53-associated Rho GDP dissociation inhibitor, is over-expressed in gene expression profiles of TP53 disrupted chronic lymphocytic leukaemia cells

Michele Dal Bo, Federico Pozzo, Riccardo Bomben, Massimo Degan, Daniela Marconi, Antonella Zucchetto, Davide Rossi, Gabriele Pozzato, Giorgio Zauli, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei

Research output: Contribution to journalLetterpeer-review

Abstract

The gene expression signature associated with TP53 mutation/deletion in chronic lymphocytic leukaemia is dominated by the under-expression of TP53 and other genes on chromosome 17p.
Original languageEnglish
Pages (from-to)596-599
Number of pages4
JournalBritish Journal of Haematology
Volume161
Issue number4
DOIs
Publication statusPublished - May 2013

Keywords

  • CLL
  • Chemosensitivity
  • TP53

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