An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris

Giovanni Appendino; Gian Cesare Tron; Giancarlo Cravotto; Giovanni Palmisano; Jasmin Jakupovic

doi:10.1021/np980218n

An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris

Giovanni Appendino
, Gian Cesare Tron
, Giancarlo Cravotto
, Giovanni Palmisano
, Jasmin Jakupovic

Research output: Contribution to journal › Article › peer-review

Abstract

A short and practical process for the isolation of ingenol (1a) from an agricultural commodity (the seeds of Euphorbia lathyris) is described. Macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the Euphorbia factors L₂ (3), L₃ (4a), and L₈ (4b) was established by 2D NMR measurements. Full spectroscopic data for these compounds are reported.

Original language	English
Pages (from-to)	76-79
Number of pages	4
Journal	Journal of Natural Products
Volume	62
Issue number	1
DOIs	https://doi.org/10.1021/np980218n
Publication status	Published - 1999
Externally published	Yes

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title = "An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris",

abstract = "A short and practical process for the isolation of ingenol (1a) from an agricultural commodity (the seeds of Euphorbia lathyris) is described. Macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the Euphorbia factors L2 (3), L3 (4a), and L8 (4b) was established by 2D NMR measurements. Full spectroscopic data for these compounds are reported.",

author = "Giovanni Appendino and Tron, \{Gian Cesare\} and Giancarlo Cravotto and Giovanni Palmisano and Jasmin Jakupovic",

year = "1999",

doi = "10.1021/np980218n",

language = "English",

volume = "62",

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journal = "Journal of Natural Products",

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publisher = "American Chemical Society",

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T1 - An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris

AU - Appendino, Giovanni

AU - Tron, Gian Cesare

AU - Cravotto, Giancarlo

AU - Palmisano, Giovanni

AU - Jakupovic, Jasmin

PY - 1999

Y1 - 1999

N2 - A short and practical process for the isolation of ingenol (1a) from an agricultural commodity (the seeds of Euphorbia lathyris) is described. Macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the Euphorbia factors L2 (3), L3 (4a), and L8 (4b) was established by 2D NMR measurements. Full spectroscopic data for these compounds are reported.

AB - A short and practical process for the isolation of ingenol (1a) from an agricultural commodity (the seeds of Euphorbia lathyris) is described. Macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the Euphorbia factors L2 (3), L3 (4a), and L8 (4b) was established by 2D NMR measurements. Full spectroscopic data for these compounds are reported.

UR - https://www.scopus.com/pages/publications/0032912055

U2 - 10.1021/np980218n

DO - 10.1021/np980218n

M3 - Article

SN - 0163-3864

VL - 62

SP - 76

EP - 79

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 1

ER -

An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris

Abstract

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