An atypical occurrence of Aspergillosis in leukemic patient: Brief description of a clinical case

L. Pastrone, M. T. Corsetti, L. Depaoli, S. Sampò, M. Colonna, A. Rocchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Herein we describe a 43 year-old Caucasian female patient with acute myeloid leukemia that developed an unconventional form of invasive Aspergillosis. For therapeutic reasons, a Groshong-type central venous catheter was positioned. Monitoring the patient's clinical conditions, positive values for C-reactive protein and galactomannan were correlated with a probably Aspergillosis. Surprisingly no pulmonary evidences were observed. Due to worsening conditions, she was re-hospitalized and a blood culture was performed, whom positivity resulted as the first clinical evidence of Aspergillus fumigatus. Further evidence about species identification was obtained by sequencing the fungal ITS region. We support the clinical value of blood culture as a decisive factor to improve the diagnosis of catheter-related Aspergillosis.

Original languageEnglish
Pages (from-to)655-658
Number of pages4
JournalJournal de Mycologie Medicale
Volume28
Issue number4
DOIs
Publication statusPublished - Dec 2018
Externally publishedYes

Keywords

  • Aspergillus fumigatus
  • Blood culture
  • CVC
  • Invasive Aspergillosis
  • Leukemia

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