Alcohol metabolism: Role in toxicity and carcinogenesis

Thomas M. Badger, Martin J.J. Ronis, Helmut K. Seitz, Emanuele Albano, Magnus Ingelman-Sundberg, Charles S. Lieber

Research output: Contribution to journalArticlepeer-review

Abstract

This article contains the proceedings of a symposium at the 2002 RSA Meeting in San Francisco, organized and co-chaired by Thomas M. Badger, Paul Shih-Jiun Yin, and Helmut Seitz. The presentations were (1) First-pass metabolism of ethanol: Basic and clinical aspects, by Charles Lieber; (2) Intracellular CYP2E1 transport, oxidative stress, cytokine release, and ALD, by Magnus Ingelman-Sundberg; (3) Pulsatile ethanol metabolism in intragastric infusion models: Potential role in toxic outcomes, by Thomas M. Badger and Martin J.J. Ronis; (4) Free radicals, adducts, and autoantibodies resulting from ethanol metabolism: Role in ethanol-associated toxicity, by Emanuele Albano; and (5) Gastrointestinal metabolism of ethanol and its possible role in carcinogenesis, by Helmut Seitz.

Original languageEnglish
Pages (from-to)336-347
Number of pages12
JournalAlcoholism: Clinical and Experimental Research
Volume27
Issue number2
DOIs
Publication statusPublished - 1 Feb 2003
Externally publishedYes

Keywords

  • Alcohol
  • Cancer
  • Gastrointestinal Tract
  • Liver
  • Metabolism
  • Toxicity

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