Accumulation of anthracyclines by a W/O microemulsion

F. Pattarino, M. R. Gasco, M. Trotta

Research output: Contribution to journalArticlepeer-review

Abstract

The capability of the disperse phase of w/o microemulsions to function as a reservoir was evidenced using doxorubicine and 1-demethoxy-daunorubicine. The diffusion of the anthracyclines from aqueous solutions to w/o microemulsions, containing lecithin as surfactant and their accumulation in the disperse phase were observed. The diffusion rate was higher for 1-demethoxy-daunorubicine than for doxorubicine
Original languageEnglish
Pages (from-to)339-344
Number of pages6
JournalFarmaco
Volume44
Issue number3
Publication statusPublished - 1989
Externally publishedYes

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