A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

P Bonfitto; V Lamorgese; Vietro T De; Mario MALERBA; L Rizzello; S Scoditti; R. Zuin

doi:10.1179/joc.1999.11.4.273

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

P Bonfitto
, V Lamorgese
, Vietro T De
, Mario MALERBA
, L Rizzello
, S Scoditti
, R. Zuin

Department of Translational Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

Original language	English
Pages (from-to)	273-277
Number of pages	5
Journal	Journal of Chemotherapy
Volume	11
Issue number	4
DOIs	https://doi.org/10.1179/joc.1999.11.4.273
Publication status	Published - 1999

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SDG 3 Good Health and Well-being

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10.1179/joc.1999.11.4.273

http://hdl.handle.net/11579/88635

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title = "A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia",

abstract = "We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.",

author = "P Bonfitto and V Lamorgese and De, \{Vietro T\} and Mario MALERBA and L Rizzello and S Scoditti and R. Zuin",

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T1 - A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

AU - Bonfitto, P

AU - Lamorgese, V

AU - De, Vietro T

AU - MALERBA, Mario

AU - Rizzello, L

AU - Scoditti, S

AU - Zuin, R.

PY - 1999

Y1 - 1999

N2 - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

AB - We compared the effectiveness and safety of ceftazidime and cefepime in hospitalized patients with community-acquired pneumonia. The 148 enrolled patients received 2 g ceftazidime three times daily or 2 g cefepime twice daily. The clinical success rate was the same for both drugs. Even the microbiological effectiveness was similar. Both drug regimens were well tolerated. We conclude that 2 g ceftazidime three times daily were as effective as 2 g cefepime twice daily for the treatment of community-acquired pneumonia in hospitalized patients. The cost of ceftazidime treatment was, however, higher than the cost of cefepime treatment.

UR - https://iris.uniupo.it/handle/11579/88635

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DO - 10.1179/joc.1999.11.4.273

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SP - 273

EP - 277

JO - Journal of Chemotherapy

JF - Journal of Chemotherapy

IS - 4

ER -

A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia

Abstract

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