TY - JOUR
T1 - A population-based study of prognostic factors in oral and oropharyngeal cancer
AU - Boffetta, P.
AU - Merletti, F.
AU - Magnani, C.
AU - Terracini, B.
N1 - Funding Information:
Acknowledgements-This study was supported by Consiglio Nazionale delle Ricerche, Rome (Progetto Finalizzato Oncologia, Contracts 85.02391.44 and 86.00595.44), Associazione Italiana per la Ricerca sul Cancro and the Italian Ministry of Education, We wish to thank Dr R. Zanetti from the Cancer Registry in Turin for helping with the definition of the study population, Dr A. Mashberg for providing the clinical form used in the study, Mr G. Ferro and MS M. Nonnato for technical help and MS A. Hanss-Cousseau for secretarial support.
PY - 1994/11
Y1 - 1994/11
N2 - Cases of oral cavity and oropharynx cancer diagnosed among the residents of Torino, Italy, between 1982 and 1984 (n = 143) were followed up to June 1990. During this period, 97 subjects (67.8%) died, 69 from oral or oropharyngeal cancer. 10 more cases died from causes possibly related to oral cancer. The overall relative 5-year survival rate was 37.2%. Men experienced a worse survival than women. No difference was shown according to age, education or occupation. Patients with smooth lesions had a poorer prognosis than those with fissured or granular lesions; no association between survival and colour, elevation, induration or bleeding from the lesion was found. Extension of the tumour and nodal involvement were strong and independent predictors of survival, but no difference was found between T1 and T2 lesions. Patients who reported a 2-3-month interval between onset of symptoms and diagnosis experienced a better survival than those with shorter or longer interval. Oropharynx cases has a better prognosis than cancers of the oral cavity.
AB - Cases of oral cavity and oropharynx cancer diagnosed among the residents of Torino, Italy, between 1982 and 1984 (n = 143) were followed up to June 1990. During this period, 97 subjects (67.8%) died, 69 from oral or oropharyngeal cancer. 10 more cases died from causes possibly related to oral cancer. The overall relative 5-year survival rate was 37.2%. Men experienced a worse survival than women. No difference was shown according to age, education or occupation. Patients with smooth lesions had a poorer prognosis than those with fissured or granular lesions; no association between survival and colour, elevation, induration or bleeding from the lesion was found. Extension of the tumour and nodal involvement were strong and independent predictors of survival, but no difference was found between T1 and T2 lesions. Patients who reported a 2-3-month interval between onset of symptoms and diagnosis experienced a better survival than those with shorter or longer interval. Oropharynx cases has a better prognosis than cancers of the oral cavity.
KW - oral cavity cancer
KW - oropharyngeal cancer
KW - prognostic factors
KW - survival
UR - http://www.scopus.com/inward/record.url?scp=0027948478&partnerID=8YFLogxK
U2 - 10.1016/0964-1955(94)90013-2
DO - 10.1016/0964-1955(94)90013-2
M3 - Article
SN - 0964-1955
VL - 30
SP - 369
EP - 373
JO - European Journal of Cancer Part B: Oral Oncology
JF - European Journal of Cancer Part B: Oral Oncology
IS - 6
ER -
