A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Riccardo Mossetti; Diego Caprioglio; Giampiero Colombano; Gian Cesare Tron; Tracey Pirali

doi:10.1039/c0ob00979b

A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Riccardo Mossetti
, Diego Caprioglio
, Giampiero Colombano
, Gian Cesare Tron
, Tracey Pirali

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

Original language	English
Pages (from-to)	1627-1631
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	9
Issue number	5
DOIs	https://doi.org/10.1039/c0ob00979b
Publication status	Published - 1 Mar 2011

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abstract = "α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.",

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AU - Caprioglio, Diego

AU - Colombano, Giampiero

AU - Tron, Gian Cesare

AU - Pirali, Tracey

PY - 2011/3/1

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AB - α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

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U2 - 10.1039/c0ob00979b

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JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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ER -

A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates

Abstract

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