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A new ursane-type triterpenoid and other constituents from the leaves of Crataegus azarolus var. aronia

  • Sarbast A. Mahmud
  • , Omar A.M. Al-Habib
  • , Serena Bugoni
  • , Marco Clericuzio
  • , Giovanni Vidari

Research output: Contribution to journalArticlepeer-review

Abstract

A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.

Original languageEnglish
Pages (from-to)1637-1639
Number of pages3
JournalNatural Product Communications
Volume11
Issue number11
DOIs
Publication statusPublished - Nov 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Aorta anti-contraction effects
  • Azarolic acid
  • Crataegus azarolus
  • Pentacyclic triterpenes
  • Rosaceae

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