A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Fuad O. Abdullah; Faiq H.S. Hussain; Marco Clericuzio; Alessio Porta; Giovanni Vidari

doi:10.1002/cbdv.201600281

A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Fuad O. Abdullah
, Faiq H.S. Hussain
, Marco Clericuzio
, Alessio Porta
, Giovanni Vidari

Department of Science and Technological Innovation

Research output: Contribution to journal › Article › peer-review

Abstract

Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

Original language	English
Article number	e1600281
Journal	Chemistry and Biodiversity
Volume	14
Issue number	3
DOIs	https://doi.org/10.1002/cbdv.201600281
Publication status	Published - 1 Mar 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cytotoxic activities
Dipsacaceae
Iridoid dimers
Kurdish medicinal plant
Pterocephalus nestorianus

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10.1002/cbdv.201600281

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title = "A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus N{\'a}b{\v e}lek",

abstract = "Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.",

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author = "Abdullah, \{Fuad O.\} and Hussain, \{Faiq H.S.\} and Marco Clericuzio and Alessio Porta and Giovanni Vidari",

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year = "2017",

month = mar,

day = "1",

doi = "10.1002/cbdv.201600281",

language = "English",

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journal = "Chemistry and Biodiversity",

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T1 - A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

AU - Abdullah, Fuad O.

AU - Hussain, Faiq H.S.

AU - Clericuzio, Marco

AU - Porta, Alessio

AU - Vidari, Giovanni

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

AB - Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

KW - Cytotoxic activities

KW - Dipsacaceae

KW - Iridoid dimers

KW - Kurdish medicinal plant

KW - Pterocephalus nestorianus

UR - https://www.scopus.com/pages/publications/85014512906

U2 - 10.1002/cbdv.201600281

DO - 10.1002/cbdv.201600281

M3 - Article

SN - 1612-1872

VL - 14

JO - Chemistry and Biodiversity

JF - Chemistry and Biodiversity

IS - 3

M1 - e1600281

ER -

A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Abstract

UN SDGs

Keywords

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