A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

Orit Kaidar-Person; Hannah M. Dahn; Alan M. Nichol; Liesbeth J. Boersma; Dirk de Ruysscher; Icro Meattini; Jean Philippe Pignol; Cynthia Aristei; Yazid Belkacemi; Dori Benjamin; Nuran Bese; Charlotte E. Coles; Pierfrancesco Franco; Alice Y. Ho; Sandra Hol; Reshma Jagsi; Anna M. Kirby; Livia Marrazzo; Gustavo N. Marta; Meena S. Moran; Henrik D. Nissen; Vratislav Strnad; Yvonne Zissiadis; Philip M. Poortmans; Birgitte V. Offersen

doi:10.1016/j.radonc.2021.09.012

A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

Orit Kaidar-Person, Hannah M. Dahn, Alan M. Nichol, Liesbeth J. Boersma, Dirk de Ruysscher, Icro Meattini, Jean Philippe Pignol, Cynthia Aristei, Yazid Belkacemi, Dori Benjamin, Nuran Bese, Charlotte E. Coles, Pierfrancesco Franco, Alice Y. Ho, Sandra Hol, Reshma Jagsi, Anna M. Kirby, Livia Marrazzo, Gustavo N. Marta, Meena S. MoranHenrik D. Nissen, Vratislav Strnad, Yvonne Zissiadis, Philip M. Poortmans, Birgitte V. Offersen

Department of Translational Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Bolus serves as a tissue equivalent material that shifts the 95–100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method.

Original language	English
Pages (from-to)	115-121
Number of pages	7
Journal	Radiotherapy and Oncology
Volume	164
DOIs	https://doi.org/10.1016/j.radonc.2021.09.012
Publication status	Published - Nov 2021

Keywords

Bolus
Breast cancer
Mastectomy
PMRT
Radiation therapy
Tissue compensator

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.radonc.2021.09.012

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Kaidar-Person, O., Dahn, H. M., Nichol, A. M., Boersma, L. J., de Ruysscher, D., Meattini, I., Pignol, J. P., Aristei, C., Belkacemi, Y., Benjamin, D., Bese, N., Coles, C. E., Franco, P., Ho, A. Y., Hol, S., Jagsi, R., Kirby, A. M., Marrazzo, L., Marta, G. N., ... Offersen, B. V. (2021). A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer. Radiotherapy and Oncology, 164, 115-121. https://doi.org/10.1016/j.radonc.2021.09.012

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title = "A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer",

abstract = "Bolus serves as a tissue equivalent material that shifts the 95–100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method.",

keywords = "Bolus, Breast cancer, Mastectomy, PMRT, Radiation therapy, Tissue compensator",

author = "Orit Kaidar-Person and Dahn, {Hannah M.} and Nichol, {Alan M.} and Boersma, {Liesbeth J.} and {de Ruysscher}, Dirk and Icro Meattini and Pignol, {Jean Philippe} and Cynthia Aristei and Yazid Belkacemi and Dori Benjamin and Nuran Bese and Coles, {Charlotte E.} and Pierfrancesco Franco and Ho, {Alice Y.} and Sandra Hol and Reshma Jagsi and Kirby, {Anna M.} and Livia Marrazzo and Marta, {Gustavo N.} and Moran, {Meena S.} and Nissen, {Henrik D.} and Vratislav Strnad and Yvonne Zissiadis and Poortmans, {Philip M.} and Offersen, {Birgitte V.}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",

year = "2021",

month = nov,

doi = "10.1016/j.radonc.2021.09.012",

language = "English",

volume = "164",

pages = "115--121",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

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Kaidar-Person, O, Dahn, HM, Nichol, AM, Boersma, LJ, de Ruysscher, D, Meattini, I, Pignol, JP, Aristei, C, Belkacemi, Y, Benjamin, D, Bese, N, Coles, CE, Franco, P, Ho, AY, Hol, S, Jagsi, R, Kirby, AM, Marrazzo, L, Marta, GN, Moran, MS, Nissen, HD, Strnad, V, Zissiadis, Y, Poortmans, PM & Offersen, BV 2021, 'A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer', Radiotherapy and Oncology, vol. 164, pp. 115-121. https://doi.org/10.1016/j.radonc.2021.09.012

TY - JOUR

T1 - A Delphi study and International Consensus Recommendations

T2 - The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

AU - Kaidar-Person, Orit

AU - Dahn, Hannah M.

AU - Nichol, Alan M.

AU - Boersma, Liesbeth J.

AU - de Ruysscher, Dirk

AU - Meattini, Icro

AU - Pignol, Jean Philippe

AU - Aristei, Cynthia

AU - Belkacemi, Yazid

AU - Benjamin, Dori

AU - Bese, Nuran

AU - Coles, Charlotte E.

AU - Franco, Pierfrancesco

AU - Ho, Alice Y.

AU - Hol, Sandra

AU - Jagsi, Reshma

AU - Kirby, Anna M.

AU - Marrazzo, Livia

AU - Marta, Gustavo N.

AU - Moran, Meena S.

AU - Nissen, Henrik D.

AU - Strnad, Vratislav

AU - Zissiadis, Yvonne

AU - Poortmans, Philip M.

AU - Offersen, Birgitte V.

PY - 2021/11

Y1 - 2021/11

N2 - Bolus serves as a tissue equivalent material that shifts the 95–100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method.

AB - Bolus serves as a tissue equivalent material that shifts the 95–100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method.

KW - Bolus

KW - Breast cancer

KW - Mastectomy

KW - PMRT

KW - Radiation therapy

KW - Tissue compensator

UR - http://www.scopus.com/inward/record.url?scp=85116580601&partnerID=8YFLogxK

U2 - 10.1016/j.radonc.2021.09.012

DO - 10.1016/j.radonc.2021.09.012

M3 - Article

SN - 0167-8140

VL - 164

SP - 115

EP - 121

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

ER -

A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

Abstract

Keywords

UN SDGs

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