From pathobioLogy to synoviA on chip: driving rheuMatoId arthritis to the precisioN medicine GOal

The EU-funded FLAMIN-GO project proposes to overcome conventional clinical trials for testing the efficacy of novel treatment modalities through the development of an organ-on-chip platform. The FLAMIN-GO approach uses patient biopsies to construct 3D models which mimic the complexity of the RA joint and can be tailored for each individual patient. The idea is to use these models for optimal drug identification in less than 2two months, offering a faster, more cost-effective and ethically sound approach for drug screening.