Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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Old dog, new tricks. Inhibiting HDACs using isonitriles. Novel epigenetic drugs against triple negative breast cancer
TRON, G. C. (PI), MANFREDI, M. (CoI), GROLLA, A. (CoI) & APRILE, S. (CoI)
AIRC - Fondazione AIRC per la Ricerca sul Cancro
2/01/24 → 31/03/29
Project: Research
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iSonitriles: innovative pHarmacOphoric GroUps as aNtibacterial agents against multidrug resistance pathogenic bacteria (SHOGUN)
TRON, G. C. (PI), APRILE, S. (CoI) & FRACCHIA, L. (CoI)
MUR - Ministero dell'Università e Ricerca
16/10/23 → 16/10/25
Project: Research
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Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy
Galli, U., Moro, M., Balestrero, F. C., Colombo, G., Koten, M., Roncaglio, B., Genazzani, A. A., Aprile, S., Massarotti, A., Orsomando, G., Pirali, T. & Grolla, A. A., 12 Mar 2026, In: Journal of Medicinal Chemistry. 69, 5, p. 5259-5290 32 p.Research output: Contribution to journal › Article › peer-review
Open Access -
An adamantane-based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation
Lamberti, A., Aprile, S., Cabañero, D., Travagin, F., Butron, L., Fernández-Ballester, G., Tron, G. C., Fernández-Carvajal, A., Ferrer-Montiel, A. & Galli, U., Jul 2025, In: FEBS Journal. 292, 13, p. 3449-3476 28 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Exploring the pharmaceutical potential of ammonium organotrifluoroborate functional group: Comprehensive chemical, metabolic, and plasma stability evaluation
Villani, S., IMPERIO, D., PANZA, L., Confalonieri, L., FALLARINI, S., APRILE, S. & DEL GROSSO, E., 2024, In: European Journal of Medicinal Chemistry. 279Research output: Contribution to journal › Article › peer-review
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Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics
Villani, S., FALLARINI, S., Rezzi, S. J., DI MARTINO, R. M. C., APRILE, S. & DEL GROSSO, E., 2024, In: Journal of Pharmaceutical and Biomedical Analysis. 237Research output: Contribution to journal › Article › peer-review
Open Access -
The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators
Lamberti, A., Serafini, M., APRILE, S., Bhela, I. P., Goutsiou, G., Pessolano, E., Fernandez-Ballester, G., Ferrer-Montiel, A., DI MARTINO, R. M. C., Fernandez-Carvajal, A. & PIRALI, T., 2024, In: European Journal of Medicinal Chemistry. 279Research output: Contribution to journal › Article › peer-review
Open Access