Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Leveraging new chemical modalities for reprogramming IDO1 half-life in cancer immunotherapy
PIRALI, T. (PI), FALLARINI, S. (CoI), DEL GROSSO, E. (CoI), MASSAROTTI, A. (CoI) & MIGGIANO, R. (CoI)
AIRC - Fondazione AIRC per la Ricerca sul Cancro
2/01/24 → 31/03/29
Project: Research
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Deciphering the mechanistic details of Mycobacterium tuberculosis nucleotide excision repair and related proteins as key players of bacterial persistence and adaptation: structure-based insights for anti-evolution drug design
MIGGIANO, R. (PI)
MUR - Ministero dell'Università e Ricerca
30/11/23 → 29/11/25
Project: Research
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Targeting opportunities presented by the pyrimidine biosynthesis pathway in Mycobacterium tuberculosis: a brief review
Alberti, M. & Miggiano, R., Jan 2026, In: Biochemical Society Transactions. 54, 1, BST20253113.Research output: Contribution to journal › Review article › peer-review
Open Access -
Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity
Alberti, M., Tamburello, M., Salamone, S., Gallinella, G., Sanna, C., Appendino, G. B., Lolli, M. L., Massarotti, A., Pollastro, F. & Miggiano, R., 28 Nov 2025, In: Journal of Natural Products. 88, 11, p. 2586-2595 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
DnaB and DciA: mechanisms of helicase loading and translocation on ssDNA
Gao, N., Mazzoletti, D., Peng, A., Olinares, P. D. B., Morrone, C., Garavaglia, A., Gouda, N., Tsoy, S., Mendoza, A., Chowdhury, A., Cerullo, A., Bhavsar, H., ROSSI, F., RIZZI, M., Chait, B. T., MIGGIANO, R. & Jeruzalmi, D., 2025, In: Nucleic Acids Research. 53, 12Research output: Contribution to journal › Article › peer-review
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Fluorescent Isostere (Fluostere) of the Carboxylate: Design of hDHODH Fluorescent Inhibitors as Proof of Concept
Sainas, S., Martino, E., Garino, C., Circosta, P., Luganini, A., Giorgis, M., Bavo, F., Piccinini, M., Ramondetti, C., Alberti, M., Miggiano, R., Gribaudo, G., Boschi, D., Frølund, B. & Lolli, M. L., 10 Jul 2025, In: Journal of Medicinal Chemistry. 68, 13, p. 13562-13590 29 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Innovative synthesis and purification method of fluorescent and bifunctional substrates for self-labelling protein tags
Sategna, A., Leoncini, M., CAPRIOGLIO, D., Mattossovich, R., MIGGIANO, R., MINASSI, A. & Merlo, R., 2025, In: Bioorganic and Medicinal Chemistry. 128Research output: Contribution to journal › Article › peer-review